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Practical Frameworks for Deploying AI in Healthcare Systems


Each minute of our life is a lesson but most of us fail to read it. I thought I would just add my daily lessons and the lessons that I learned by seeing the people around here. So it may be useful for you and as memories for me.

Over the last several years working in healthcare technology, I’ve had a front-row seat to the industry’s growing relationship with artificial intelligence. From primary care analytics and NHS interoperability work to leading AI-driven product development, I’ve watched organisations move from curiosity to urgency. Today, everyone—from commissioners to clinicians to software vendors—is trying to figure out how to incorporate AI into their workflows, transform patient experience, or simply avoid falling behind.

But the truth is more complicated: healthcare is adopting AI faster in ambition than in capability. I’ve seen teams want “an AI solution” before fully understanding the problem. I’ve watched pilots stall because the workflow wasn’t ready, governance wasn’t aligned, or the data simply couldn’t support the outcome. I’ve also seen the opposite—cases where well-structured frameworks led to safe, meaningful, and measurable improvements in clinical care and operational efficiency.

AI is not ruling healthcare; it’s reshaping the foundations we build on. And in this rush, the organisations that succeed aren’t the ones using the most sophisticated models, but the ones using the most disciplined frameworks.

That’s why I consistently return to a core set of AI frameworks. They anchor the excitement, provide guardrails for safety and governance, and force clarity on what we are actually trying to achieve. In my own work—whether integrating SmartLife products with NHS systems through IM1, shaping data-driven decision tools, or preparing analytics platforms for AI-powered features—these frameworks have proven invaluable.

Healthcare loves acronyms almost as much as it needs transformation. Every week, someone asks me the same question: “Where do we even start with AI in our organisation?”

It’s the right question—but often the wrong mindset. Many leaders assume AI adoption is a single decision, when in reality it’s a layered change-management journey involving clinical safety, governance, workflow redesign, regulatory alignment, analytics infrastructure, and—most underestimated of all—human behaviour.

Working across primary care data platforms, NHS integrations (IM1, PFS, Bulk Extract), analytics products, and clinical pathways, I’ve learned that choosing the right frameworks is less about picking the trendiest one and more about clarifying what problem you’re actually solving. Are you validating an early prototype? Deploying an AI decision-support tool? Creating an enterprise AI strategy? Evaluating risk? Measuring real-world impact?

Different problems require different lenses.

Below is a curated, experience-tested set of frameworks I use when guiding organisations through AI adoption—from ideation to implementation to evaluation. I’ve added commentary on how each aligns with real operational constraints we face in the NHS and primary care.

This article outlines 12 AI frameworks I rely on and why they matter. Whether you’re evaluating your first model or planning a system-wide adoption strategy, these will help you cut through the hype and focus on what works.

1. ELCAP: ESMO Guidance for Large Language Models in Clinical Practice

A pragmatic guide for clinically safe use of LLMs.

Where it helps in practice:

Use this as your clinical acceptance criteria when piloting GPT-style tools for triage, documentation, coding support, or patient communication. It’s strong at articulating risks clinicians care about (hallucination, ambiguity, trust).

2. QUEST: Human Evaluation Framework for LLMs in Healthcare

Focuses on human–AI interaction quality.

Why it matters operationally:

Most AI failures aren’t algorithmic—they’re behavioural. QUEST is excellent for assessing whether staff can meaningfully use your tool and whether it improves decision clarity rather than adding cognitive load.

3. FUTURE-AI: Best Practices for Trustworthy Medical AI

A gold-standard reference for governance, fairness, transparency, and safety.

My take as a product lead:

This is where your SCAL, DPIA, clinical safety case, and hazard logs belong. It gives your governance team a shared vocabulary and stops “trust” from becoming a buzzword.

4. TEHAI: Evaluation Framework for Implementing AI in Healthcare Settings

A structured evaluation framework for assessing readiness and impact.

In the real world:

TEHAI helps you pressure-test whether your AI system can survive the organisational ecosystem—data flows, workflow integration, interoperability, clinical oversight, commissioning requirements, etc.

Good to use before an ICB deployment or scaling beyond a pilot practice.

5. DECIDE-AI: Guideline for Early Clinical Evaluation of AI Decision Support Systems

Designed for early-stage testing and feasibility assessments.

When I use it:

During prototype and pilot phases—especially when validating AI-driven recommendations, personalised care plans, risk scores, or decision trees before exposing clinicians to them.

6. SALIENT: Framework for End-to-End Clinical AI Implementation

One of the few frameworks that covers reality end-to-end.

Why it’s underrated:

It doesn’t just say “implement AI”—it shows the sequence:

data → model → workflow → evaluation → monitoring → governance.

It’s closest to how I run AI integration projects in practice.

7. AI Evidence Pathway for Trustworthy AI in Health

A more policy-oriented framework championed for national-scale deployments.

Where it fits:

Essential for organisations engaging with NHS England, regulators, ICBs, or multi-site implementations. Strong alignment with UK assurance processes.

8. FURM: Evaluating Fair, Useful, and Reliable AI Models in Health Systems

A deceptively simple but powerful framing.

Why leaders should care:

Most organisations over-index on accuracy, under-index on fairness, and ignore usefulness entirely. FURM centres actual clinical and operational utility.

9. IMPACTS Framework: Evaluating Long-Term Real-World AI Effects

Focuses on post-deployment—where most frameworks end prematurely.

Critical insight:

The goal isn’t to launch AI. The goal is to sustain value and avoid regressions. IMPACTS helps measure whether your deployed solution meaningfully changes outcomes, costs, or experience.

10. Process Framework for Successful AI Adoption in Healthcare

A meta-framework showing the organisational capabilities required:

stakeholder alignment, workflow fit, policy readiness, training, trust-building.

My take:

This is the antidote to “AI as an IT project.” AI success is organisational, not technical.

11. The “3L Model”: Latency, Liability, and Literacy

A brutally practical test before deploying any AI tool in a real clinical environment.

Ask:

  1. Latency – Is the AI fast enough to fit the workflow? Slow = unusable.
  2. Liability – Who is accountable for the decision? If the answer is unclear, the deployment is premature.
  3. Literacy – Do staff understand what the AI can’t do? Most clinicians don’t need to know how AI works—but they must know where its limits lie.

This model has saved several projects I’ve worked on from misaligned expectations.

12. The “Integration Trifecta”: Data → Workflow → Governance

Every AI implementation that fails usually breaks on one of these:

  1. Data: Is the data clean, real-time, coded, and interoperable?
  2. Workflow: Does it reduce clicks, not add them?
  3. Governance: Is safety, oversight, and auditability built in from day one?

In our IM1 and SCAL work, this trifecta is the backbone:

data extraction and mapping, API integration, safety case review, hazard logging, and clinical sign-off all flow through these gates.

What I’ve Learned Building AI in Healthcare

Leading AI initiatives in primary care analytics and NHS interoperability has taught me a few uncomfortable truths:

  • Most organisations want AI but haven’t articulated the problem it should solve.
  • Governance teams want safety; clinicians want usefulness; leadership wants ROI. AI rarely satisfies all three at once without deliberate design.
  • You cannot “bolt on” AI to a broken workflow—AI amplifies workflow issues.
  • The gap between pilot success and system-wide adoption is bigger than most leaders predict.
  • Evaluation frameworks don’t replace judgement—they sharpen it.

Frameworks don’t give you answers; they give you structure. The thinking still has to be yours.

Which Framework Should You Start With?

Here’s a simple test:

  • Building a prototype? → DECIDE-AI + QUEST
  • Preparing for pilot? → SALIENT + TEHAI
  • Aiming for clinical deployment? → ELCAP + FUTURE-AI
  • Scaling across an ICB or enterprise? → AI Evidence Pathway + IMPACTS
  • Ensuring fairness and trust? → FURM
  • Want an operational sanity check? → Integration Trifecta + 3L Model

If you wanna share your experiences, you can find me online in all your favorite places  LinkedIn and Facebook. Shoot me a DM, a tweet, a comment, or whatever works best for you. I’ll be the one trying to figure out how to read books and get better at playing ping pong at the same time.

 
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Posted by on December 2, 2025 in Experiences of Life.

 

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Why Healthcare IT Graveyard Is Getting Crowded


Each minute of our life is a lesson but most of us fail to read it. I thought I would just add my daily lessons and the lessons that I learned by seeing the people around here. So it may be useful for you and as memories for me.

I’ve spent more than a decade building healthcare products across Europe, Asia, and the U.S. I’ve led Quality, Product, and Delivery at scale. I’ve watched companies grow explosively, and I’ve watched companies vanish overnight literally.

And after 15 years working in healthcare, the pattern is painfully clear:

Healthcare tech doesn’t fail because of weak engineering. It fails because founders fundamentally misunderstand healthcare.

Here’s the uncomfortable truth — backed by recent, spectacular collapses.

The Graveyard Is Getting Crowded

These aren’t small startups. These were the darlings of global healthcare tech:

  • Forward Health – $660M raised, shut down with zero patient transition
  • Olive AI – $850M raised, sold for parts after failing to justify ROI
  • Babylon Health – $4B valuation, blew up across multiple continents
  • Pear Therapeutics – FDA-cleared digital therapeutics, bankrupt
  • Quibi of Healthcare: Haven (Amazon–JPM–Berkshire) – shut down despite unlimited resources
  • Google Health (v1) – closed after failing to reach provider adoption
  • Microsoft HealthVault – shut down due to low user engagement and system complexity
  • Sense.ly (AI nurse avatar) – essentially disappeared after poor provider uptake
  • 23andMe Therapeutics spinout – quietly scaled back after no viable clinical revenue stream
  • Walgreens / Theranos fallout – major proof that hype beats due diligence in this sector
  • Proteus Digital Health (smart pill) – raised $500M, then bankrupt
  • Practice Fusion – sold for pennies after criminal investigations and failed EHR monetization
  • ZocDoc expansion failure – pivoted multiple times after failing to win provider-side economics
  • Oscar Health (several failed geographic launches) – struggled due to regulatory economics
  • IBM Watson Health – $3B+ investment, divested for $1B after clinical failures

This list is long. And growing.

The Core Misunderstanding: Healthcare Is Not a Tech Problem

Engineering-driven founders consistently misdiagnose the domain.

They believe healthcare = complex workflows + messy data + outdated UI.

Solve that and… success.

But healthcare is not a systems problem.

It is a trust problem wrapped in regulation, economics, and risk.

  • Lives are at stake — not convenience.
  • Medical decisions require validated evidence — not beta features.
  • Clinicians rely on reliability and accountability — not iteration velocity.
  • Patients don’t adopt new care models without months or years of trust-building.

Every failed company ignored these constraints.

The Integration Trap: The Silent Killer

This is where most companies die.

Healthcare runs on a brittle spine of EMRs, APIs, and legacy systems.

If you don’t integrate, you don’t exist.

  • Forward’s CarePods were genuinely innovative. But without seamless EMR connections, they became operationally useless.
  • Olive AI automated tasks internally… but could not standardize ROI across EMRs.
  • IBM Watson Health promised AI-driven oncology decisions. But the recommendations were inconsistent with evidence-based guidelines.

The rule:

If you don’t reduce workload inside the existing workflow, clinicians will ignore you.

No integration = no adoption.

No adoption = no revenue.

No revenue = shutdown.

Why Consumer Tech Logic Fails in Healthcare

Tech founders try to import playbooks from SaaS, marketplaces, and fintech:

  • “Move fast and break things”
  • “Launch MVP, iterate later”
  • “Acquire users, figure out monetization later”
  • “Data is the new oil”
  • “AI will replace inefficiencies”

These logics collapse immediately in healthcare:

  1. Healthcare data is not clean; 80% is unstructured.
  2. Interoperability is not an optional feature — it is the foundation.
  3. Clinicians require evidence, not velocity.
  4. Patients are not early adopters; they are risk-averse by necessity.

The market punishes anyone who treats healthcare like another consumer vertical.

The Reimbursement Illusion: Where Startups Bleed Out

This is the part Silicon Valley consistently ignores.

In healthcare, value is NOT determined by the end user.

Value is determined by:

  • payors
  • reimbursement codes
  • medical necessity rules
  • regulatory status
  • clinical outcomes data

A product can delight users and still die if:

  • there’s no CPT code
  • insurers won’t reimburse
  • the product doesn’t reduce provider workload
  • there’s no proven cost savings

Olive AI is the textbook example.

Automation sounded brilliant — but if hospitals can’t bill for it, the business collapses.

Pear Therapeutics had FDA clearance, efficacy data, and clinical logic.

Still died because payors refused to reimburse at scale.

Healthcare economics — not innovation — determine survival.

What Actually Works (and Why It Looks “Unsexy”)

The successful products in healthcare are almost never glamorous:

  • Automated population stratification
  • Scheduling optimization
  • Revenue cycle improvements
  • Medication adherence
  • Secure messaging
  • Chronic disease workflows
  • Interoperability middleware
  • Claims cleaning and fraud detection

Unsexy wins because it integrates, it reduces workload, it fits reimbursement, it avoids clinical risk, and it solves one painful problem extremely well.

The companies that succeed do the following:

  • Integrate seamlessly with EMRs
  • Prove ROI early
  • Reduce clicks, not add them
  • Earn clinical champions, not marketing awards
  • Build for the system as it is, not the system they wish existed
  • Grow slowly but sustainably — not explosively and unsafely

Healthcare rewards evolution, not revolution.

Forward Health’s Shutdown Is the Perfect Case Study

Forward turned off the lights overnight:

  • No transition pathway
  • Canceled appointments
  • Patients left stranded
  • Systems turned off immediately

This is what happens when a company:

  • optimizes for investor excitement instead of clinical safety
  • designs for TechCrunch instead of clinicians
  • prioritizes disruption over integration
  • treats healthcare as a retail subscription business instead of a regulated service

Patients pay the real cost of these failures.

The Real Pattern Behind Every Healthcare Tech Collapse

Let’s stop pretending these are isolated incidents.

The failures follow the same template:

  1. Overpromise with polished demos
  2. Underestimate the complexity of clinical workflows
  3. Blow capital on growth before solving integration
  4. Fail to secure reimbursement pathways
  5. Struggle to prove clinical and financial ROI
  6. Lose trust from clinicians
  7. Run out of money
  8. Collapse suddenly
  9. Patients and providers are left scrambling

Money and engineering talent are not substitutes for:

  • clinical insight
  • regulatory design
  • healthcare economics
  • trust-building
  • real-world workflow alignment

The Hard Truth

Healthcare rewards reliability over innovation.

Simple solutions outperform brilliant ones.

Integration beats disruption every time.

I’ve watched billion-dollar firms fail and small scrappy teams succeed.

The winners understood healthcare is a trust-based, evidence-driven system.

The losers thought they could brute force the market with capital and code.

They were wrong.

Your Turn

What healthcare product promised everything and delivered nothing?

If you wanna share your experiences, you can find me online in all your favorite places  LinkedIn and Facebook. Shoot me a DM, a tweet, a comment, or whatever works best for you. I’ll be the one trying to figure out how to read books and get better at playing ping pong at the same time.

 
 

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